Development of simplified new mass spectrometric technique using laser and graphene

A technology that can obtain high-resolution, micrometer-sized images for mass spectrometric analysis without sample preparation has been developed. DGIST Research Fellow Jae Young Kim and Chair-professor Dae Won Moon’s team succeeded in developing the precise analysis and micrometer-sized imaging of bio samples using a small and inexpensive laser.

DGIST announced that Research Fellow Jae Young Kim in the Department of Robotics Engineering and Chair-professor Dae Won Moon’s team developed a technology that can analyze experiment samples without any preparation processing. Due to its ability to obtain high-resolution mass spectrometric images without an experimental environment using ‘continuous wave laser’, the technology is expected to be applied widely in the precise medicine and medical diagnosis fields.

Many advance preparations are needed for the mass spectrometric imaging of biometric samples using ‘specimen,’ which thinly cut an object to analyze. The specimen must be changed artificially since they cannot be analyzed accurately in a room temperature or atmospheric pressure. To develop a convenient analysis technology and ease the burden, Research Fellow Kim started the research.

The research team installed a lens carrying continuous wave laser right below a microscope substrate where the specimen is put and shot the laser on it to measure mass spectra by examining molecules from desorption. Read full article here.


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